The Prospects of Application of Microfluidics for Synthesis of Compounds from the Alkylene Guanidine Series

Alkylene guanidines possess prominent antiseptic properties together with low toxicity; however, their use as pharmaceutical substances is limited for a series of reasons, one of which is a high concentration of impurities. The presented work considers the possibilities of application of microfluidi...

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Bibliographic Details
Published in:Polymer science. Series D, Glues and sealing materials Glues and sealing materials, 2021, Vol.14 (2), p.305-311
Main Authors: Ivanov, I. S., Kedik, S. A., Shatalov, D. O., Legon’kova, O. A., Aidakova, A. V., Norin, A. M., Khar’kovskaya, M. D.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Guanidines
Microfluidics
Polymer Sciences
Synthesis
Toxicity
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Summary:Alkylene guanidines possess prominent antiseptic properties together with low toxicity; however, their use as pharmaceutical substances is limited for a series of reasons, one of which is a high concentration of impurities. The presented work considers the possibilities of application of microfluidic synthesis for obtaining highly purified salts of alkylene guanidines suitable for use in pharmaceutics.
ISSN:1995-4212
1995-4220
DOI:10.1134/S1995421221020088