P09 Assessing vitamin E status in parental nutrition (PN) population in accordance to ESPGHAN guidance: Comparing serum vitamin E levels to vitamin E:cholesterol ratio

IntroductionESPGHAN guidance recommends measuring both serum vitamin E and its lipid ratio to accurately monitor vitamin E status amongst paediatric patients on PN. Alpha-tocopherol, the surrogate marker for vitamin E, is affected by lipid levels and as concentrations rise, vitamin E deficiency can...

Full description

Saved in:
Bibliographic Details
Published in:Frontline gastroenterology 2021-04, Vol.12 (Suppl 1), p.A16-A17
Main Authors: Vanker, Helen, Morris, Timothy James, Fagbemi, Andrew, Kadir, Ahmed
Format: Article
Language:English
Subjects:
Cholesterol
Gallbladder diseases
Lipids
Pediatrics
Population
Vitamin E
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:IntroductionESPGHAN guidance recommends measuring both serum vitamin E and its lipid ratio to accurately monitor vitamin E status amongst paediatric patients on PN. Alpha-tocopherol, the surrogate marker for vitamin E, is affected by lipid levels and as concentrations rise, vitamin E deficiency can be missed. Vitamin E deficiency can result in neurological sequalae. With cases reported in children with chronic cholestasis with normal vitamin E level but low vitamin E:cholesterol ratio. To our knowledge this is the first study evaluating the impact of these recommendations.MethodIn February 2020, at Royal Manchester Children’s Hospital, 34 children (
ISSN:2041-4137
2041-4145
DOI:10.1136/flgastro-2021-bspghan.20