In situ growth of covalent organic frameworks TpBD on electrode for electrochemical determination of aflatoxin M1

An in situ growth strategy for construction of covalent organic frameworks (COFs) TpBD on glassy carbon electrode using p-aminobenzoic acid and ethylenediamine as connector is introduced. The fabricated electrode was used for electrochemical biosensing of aflatoxin M1 in milk samples combined with m...

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Bibliographic Details
Published in:Journal of electroanalytical chemistry (Lausanne, Switzerland) Switzerland), 2021-01, Vol.881, p.114931, Article 114931
Main Authors: Guo, Lu-Lu, Wang, Yi-Ying, Pang, Yue-Hong, Shen, Xiao-Fang, Yang, Nian-Ci, Ma, Yun, Zhang, Yi
Format: Article
Language:English
Subjects:
Aflatoxin M1
Biosensors
Covalence
Covalent organic frameworks
Electrochemical biosensor
Electrode
Electrodes
Ethylenediamine
Glassy carbon
In situ growth
Nanoparticles
Room temperature
Selectivity
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Summary:An in situ growth strategy for construction of covalent organic frameworks (COFs) TpBD on glassy carbon electrode using p-aminobenzoic acid and ethylenediamine as connector is introduced. The fabricated electrode was used for electrochemical biosensing of aflatoxin M1 in milk samples combined with magnetic nanoparticles, which acted as probe carriers. The developed electrochemical biosensor exhibited high selectivity and sensitivity toward aflatoxin M1 with a detection limit of 0.15 ng/mL (S/N = 3). Moreover, the covalent bonding of TpBD on the glassy carbon electrode has good stability, which retained 76% of the initial signal after 15 days storage at room temperature. This work provides a valuable case for in situ growth of COFs TpBD on the electrode, and the proposed synthetic route is expected to provide a powerful tool for the wide application of other functional COFs in electrochemical biosensor. •Covalent organic frameworks TpBD was grown in situ on the electrode.•The modified TpBD electrode possesses an excellent stability.•The electrochemical biosensor was developed for the determination of aflatoxin M1 in milk.
ISSN:1572-6657
1873-2569
DOI:10.1016/j.jelechem.2020.114931