Fatty liver index is associated with the risk of testosterone deficiency in aging men without metabolic syndrome

Objectives Non‐alcoholic fatty liver disease (NAFLD) is suggested to be a precursor of metabolic syndrome (MetS) and could influence the risk of testosterone deficiency (TD). Fatty liver index (FLI) is a simple and useful screening tool for NAFLD. We determined the association between the risk of NA...

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Bibliographic Details
Published in:Andrology (Oxford) 2021-05, Vol.9 (3), p.863-872
Main Authors: Liu, Chia‐Chu, Huang, Shu‐Pin, Hsieh, Tusty‐Jiuan, Lee, Cheng‐Hsueh, Cheng, Kai‐Hung, Huang, Tsung‐Yi, Geng, Jiun‐Hung, Li, Ching‐Chia, Wu, Wen‐Jeng, Lee, Yung‐Chin
Format: Article
Language:English
Subjects:
Aging
aging men
fatty liver index
Insulin resistance
Medical screening
Metabolic syndrome
non‐alcoholic fatty liver disease
Population-based studies
Testosterone
testosterone deficiency
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Summary:Objectives Non‐alcoholic fatty liver disease (NAFLD) is suggested to be a precursor of metabolic syndrome (MetS) and could influence the risk of testosterone deficiency (TD). Fatty liver index (FLI) is a simple and useful screening tool for NAFLD. We determined the association between the risk of NAFLD assessed by FLI and TD in aging Taiwanese men, especially those without MetS. Materials and Methods A free health screening program was conducted for men (age: >40 years) in a medical center in Kaohsiung, Taiwan. All participants underwent a physical examination; answered a questionnaire assessing demographics, medical history, and clinical symptoms of TD; and provided 20‐mL whole blood samples for biochemical, adipocytokine, and hormonal evaluations. The risk of NAFLD was evaluated using FLI. The presence of NAFLD was ruled out if FLI value was
ISSN:2047-2919
2047-2927
DOI:10.1111/andr.12979