Biological and Chemical Assessment of Ochrosia elliptica Labill Leaves

Ochrosia elliptica Labill is a small tropical evergreen tree native to Oceania belonging to the Apocynaceae family. Eight alkaloids, two flavonoid glycosides and three phenolic acids were identified by LC/MS analysis. On the other hand, the quality and uniformity of the plant leaves were assessed th...

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Bibliographic Details
Published in:Arabian journal for science and engineering (2011) 2021-06, Vol.46 (6), p.5247-5255
Main Authors: El-Shiekh, Riham A., Al-Mahdy, Dalia A., Hifnawy, Mohamed S., Abdel-Sattar, Essam
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
Ashes
Butanol
Engineering
Flavone glycosides
Flavonoids
Fungicides
Humanities and Social Sciences
Moisture content
multidisciplinary
Phenolic acids
Research Article-Biological Sciences
Science
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Summary:Ochrosia elliptica Labill is a small tropical evergreen tree native to Oceania belonging to the Apocynaceae family. Eight alkaloids, two flavonoid glycosides and three phenolic acids were identified by LC/MS analysis. On the other hand, the quality and uniformity of the plant leaves were assessed through the determination of the total phenolic and flavonoid, in addition to total ash, acid-insoluble ash, water-soluble ash and moisture content. The total ethanolic and aqueous extracts of the leaves of O. elliptica as well as their fractions were investigated for their antinociceptive (analgesic) using tail-flick test and antimicrobial activities using agar well diffusion assay. Among the tested fractions, the results showed that the n -butanol fraction exhibited high potency as antinociceptive compared to indomethacin drug and as antifungal compared to amphotericin B.
ISSN:2193-567X
1319-8025
2191-4281
DOI:10.1007/s13369-020-04986-6