Forewarned is forearmed: chronic spontaneous urticaria as a potential risk to effective SARS‐CoV‐2 vaccine uptake and global public health

Chronic spontaneous urticaria and angioedema (CSU/A) is a common condition with an estimated global point prevalence of 0.7% (95% C.I, 0.2-1.4)(1), higher in non-White populations. Symptoms present as an 'allergy mimic' but are underpinned by non-specific, non-IgE-mediated mast cell histam...

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Bibliographic Details
Published in:British Journal of Dermatology 2021-10, Vol.185 (4), p.838-839
Main Authors: Bermingham, W.H., Ardern‐Jones, M.R., Huissoon, A.P., Krishna, M.T.
Format: Article
Language:English
Subjects:
Correspondence
Public health
Severe acute respiratory syndrome coronavirus 2
Urticaria
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Summary:Chronic spontaneous urticaria and angioedema (CSU/A) is a common condition with an estimated global point prevalence of 0.7% (95% C.I, 0.2-1.4)(1), higher in non-White populations. Symptoms present as an 'allergy mimic' but are underpinned by non-specific, non-IgE-mediated mast cell histamine release. The combination of common population prevalence and likelihood of vaccines precipitating symptoms in those with CSU/A presents an immediate risk to the SARS-COV-2 global vaccine program.
ISSN:0007-0963
1365-2133
DOI:10.1111/bjd.20495