A Short Review on Structures and Synthesis of some Heterocyclic Compounds

Some of the natural products e.g., antibiotics such as penicillin's, cephalosporin; alkaloids such as vinblastine, morphine, reserpine etc. have heterocyclic moiety.1,4 Heterocyclic compounds are broadly spread in nature and vital to life; they play a dynamic role in the metabolism of all livin...

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Bibliographic Details
Published in:Asian Journal of Research in Chemistry 2021-03, Vol.14 (2), p.149-151
Main Authors: Shaikh, Azam Z, Jadhav, Harsha, Borse, Darshana M, Jain, Ritik S
Format: Article
Language:English
Subjects:
Aluminum oxide
Ammonia
Antibiotics
Butanediol
Cancer
Catalysts
Cephalosporins
Chemistry
Cobalt
Colon
Corrosion inhibitors
Designers
Distillation
Heterocyclic compounds
Hydrocarbons
Laboratories
Liquid phases
Metabolism
Morphine
Natural products
Nickel
Nitrogen
Penicillin
Pharmaceuticals
Pyrrolidine
Reserpine
Sanitizers
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Summary:Some of the natural products e.g., antibiotics such as penicillin's, cephalosporin; alkaloids such as vinblastine, morphine, reserpine etc. have heterocyclic moiety.1,4 Heterocyclic compounds are broadly spread in nature and vital to life; they play a dynamic role in the metabolism of all living cells. Indole-3carbinol is used for prevention of breast cancer, colon cancer, and other types of cancer.12,13,14,15,16,17 Pyrrole Pyrrole is a colorless volatile liquid that blackens readily upon exposure to air, and is typically purified by distillation immediately before use. Synthesis: Pyrrolidine is prepared industrially by the reaction of 1,4-Butanediol and ammonia at a temperature of 165- 200°C and a pressure of 17-21 MPa in the presence of a cobalt- and nickel oxide catalyst, which is supported on alumina.18,19,20 The reaction is carried out in the liquid phase in a continuous tube- or tube bundle reactor, which is operated in the cycle gas method.21,22 Received on 28.01.2021 Modified on 06.02.2021 Accepted on 12.02.2021 ©AJRC All right reserved Asian J. Research Chem. 2021; 14(2):149-151.
ISSN:0974-4169
0974-4150
DOI:10.5958/0974-4150.2021.00028.6