Synthesis, characterization, and biological activity of silver nanoparticles synthesized from Aristolochia bracteolata lam

The aim of this research is to analyze the antimicrobial activity and cytotoxicity of biologically synthesized silver nanoparticles against A549 cancer cell line. Silver nanoparticles were synthesized from the leaf extract of Aristolochia bracteolata. For the characterization of silver nanoparticles...

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Bibliographic Details
Published in:Pharmacognosy Magazine 2020-07, Vol.16 (71), p.568-573
Main Authors: Sreeharsha, Nagaraja, Kathiravan, Govindarajan, Rajagopal, Kalyanaraman, Rajasekar, Arvindganth, Rajangam, Bose, Aldhubiab, Bandar, Narayanaswamy, Venugopala, Attimarad, Mahesh, Nair, Anroop, Karnathi, Rajith, Meravanige, Girish, Chandur, Uma, Roopashree, Teeka, Haroun, Micheline, Tratrat, Christophe
Format: Article
Language:English
Subjects:
Antimicrobial agents
EDTA
Fourier transforms
Gold
Herbal medicine
High performance liquid chromatography
Laryngeal cancer
Nanoparticles
Silver
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Summary:The aim of this research is to analyze the antimicrobial activity and cytotoxicity of biologically synthesized silver nanoparticles against A549 cancer cell line. Silver nanoparticles were synthesized from the leaf extract of Aristolochia bracteolata. For the characterization of silver nanoparticles, Fourier transform infrared, high-performance liquid chromatography, and ultraviolet techniques were adopted. The silver nanoparticle was found to show better antimicrobial activity when compared to the crude extract of the plant. Noteworthy cytotoxic effects against A549 cell line were shown by the nanoparticles derived from the plant extract. Following the potential of biologically synthesized silver nanoparticles, they can be a valuable addition to the treatment of human laryngeal carcinoma and can be categorized as a potent anticancer agent.
ISSN:0973-1296
0976-4062
DOI:10.4103/pm.pm_313_20