Analysis methods for medications improving cerebral circulation

• Published in: Research journal of pharmacy and technology 2021-01, Vol.14 (1), p.115-121
• Main Authors: Pashanova, Olga V., Ermakov, Dmitriy A., Philippova, Alla V., Tikhonova, Yuliya A., Pronkin, Nikolay N.
• Format: Article
• Language: English
• Subjects: Anticoagulants; Aspirin; Atherosclerosis; Brain research; Comparative analysis; Disease prevention; Endothelium; Health care; Hypertension; Mortality; Pathogenesis; Performance evaluation; Physiology; Stroke
• ISSN: 0974-3618; 0974-360X; 0974-306X
• DOI: 10.5958/0974-360X.2021.00021.4

Diseases associated with cerebral circulation disorders are among the most dangerous in the adult population1,2. [...]stroke incidence in the world averages 3 cases per 100.000 population3. Cerebral circulation disease is characterized by persistent changes in general and focal brain functions, which increase the risk of disability or death. [...]brain lesions associated with vascular dysfunction are considered as a major factor in adult mortality12. The risk factors of vascular malformations are quite widespread and include behavioral aspects like nervous exaggerations or stressful situations, and physiological like inadequate physical activity, smoking, excessive alcohol consumption, or fat and carbohydrates abundance in nutrition. According to World Health Organization, stroke is one of the most common epidemiological diseases widely spread in the world21 assuming high mortality and disability rates. [...]one in five patients is unable to move on his own, about one-third need external assistance, and only 20% can resume full employment22.