Evaluation of Anti-inflammatory and Anti-arthritic activity of Luffa acutangula peel extract mediated ZnO nanoparticles

The special improved characteristics and different application of zinc oxide nanoparticles made them to play a major role among metal oxide nanoparticles. Zinc oxide nanoparticles were successfully synthesized in a cost effective, time saving and safety method using Luffa acutangula peel extract. Zi...

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Bibliographic Details
Published in:Research journal of pharmacy and technology 2021-04, Vol.14 (4), p.2004-2008
Main Authors: Ananthalakshmi, R., Raja Rathinam, S. R. Xavier, Sadiq, A. Mohamed
Format: Article
Language:English
Subjects:
Biosynthesis
Blood
Experiments
Nanoparticles
Nitrates
Nonsteroidal anti-inflammatory drugs
Proteins
Zinc oxides
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Summary:The special improved characteristics and different application of zinc oxide nanoparticles made them to play a major role among metal oxide nanoparticles. Zinc oxide nanoparticles were successfully synthesized in a cost effective, time saving and safety method using Luffa acutangula peel extract. Zinc oxide nanoparticles showed maximum absorption peak at 377.77nm in UV visible absorption spectroscopic studies. The fourier transform infrared spectroscopy (FTIR) studies revealed the presence of various functional groups attributed by aqueous peel extract along with the zinc oxide nanoparticles. The shape of the zinc oxide nanoparticles was found to be spherical under scanning electron microscopy and they were found to be agglomerated. The zinc oxide nanoparticles prepared using Luffa acutangula showed anti-inflammatory activity when studied by Human RBC membrane stabilization method. Also they effectively inhibited the egg albumin and bovine serum albumin denaturation by which they are confirmed to have anti-arthritic activity.
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.52711/0974-360X.2021.00355