Extracellular Vesicles of Pluripotent Stem Cells

The review article presents data on extracellular vesicles (EV), bilayer phospholipid membrane structures which are secreted by different cell types and contain proteins, lipids, and nucleic acids. The features of their structure, biogenesis, and mechanisms of interaction with the recipient cell are...

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Bibliographic Details
Published in:Russian journal of developmental biology 2021-05, Vol.52 (3), p.129-140
Main Authors: Suprunenko, E. A., Sazonova, E. A., Vasiliev, A. V.
Format: Article
Language:English
Subjects:
80 Years of the Department of Embryology
Animal Anatomy
Biomedical and Life Sciences
Cell differentiation
Developmental Biology
Embryo cells
Extracellular vesicles
Histology
Life Sciences
Lipids
Membrane vesicles
Morphology
Moscow State University
Phospholipids
Pluripotency
Stem cells
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Summary:The review article presents data on extracellular vesicles (EV), bilayer phospholipid membrane structures which are secreted by different cell types and contain proteins, lipids, and nucleic acids. The features of their structure, biogenesis, and mechanisms of interaction with the recipient cell are considered. The properties of extracellular vesicles of embryonic stem cells (ESCs) and their role in the regulation of developmental processes are also considered. Special attention is paid to the vesicles of induced pluripotent stem cells (iPSCs), their role in maintaining pluripotency, and the properties of the vesicles of cells obtained during the directed differentiation of iPSCs.
ISSN:1062-3604
1608-3326
DOI:10.1134/S1062360421030073