Chlamydia Psittaci Strains from Broiler Chickens Induce Histopathological Lesions and Mortality in SPF Chickens

A detailed study on histopathological lesions induced by two outer membrane protein A ( ) genotype B strains (10/423 and 10/525) and one genotype D strain (10/298) in experimentally infected (aerosol) specific pathogen free (SPF) chickens was performed. The strains were derived from Belgian and Fren...

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Bibliographic Details
Published in:Bulletin of the Veterinary Institute in Puławy 2015-03, Vol.59 (1), p.43-50
Main Authors: Yin, Lizi, Kalmar, Isabelle, Chiers, Koen, Debyser, Isolde, Vanrompay, Daisy
Format: Article
Language:English
Subjects:
Bronchitis
chicken
Chlamydia
Conjunctivitis
Enteritis
Genotype & phenotype
Genotypes
Hepatitis
histopathology
Lesions
Membrane proteins
Mortality
Nephritis
Pathogens
Pneumonitis
Poultry
Rhinitis
Sinusitis
Specific pathogen free
Strains (organisms)
Tracheitis
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Summary:A detailed study on histopathological lesions induced by two outer membrane protein A ( ) genotype B strains (10/423 and 10/525) and one genotype D strain (10/298) in experimentally infected (aerosol) specific pathogen free (SPF) chickens was performed. The strains were derived from Belgian and French commercially raised broilers with pneumonia. Both genotype B and D strains induced conjunctivitis, rhinitis, sinusitis, tracheitis, bronchitis, pneumonitis, airsacculitis, splenitis, hepatitis, nephritis, and enteritis in sequentially (days 2 to 34 post infection) euthanized chickens. Inflammation of the ovaries was only observed in genotype D infected chickens. Overall, the genotype D strain caused more severe gross and histopathological lesions and mortality (54.5%) early upon infection. The genotype D strain seemed to replicate faster as severity of the lesions increased more quickly. is a primary pathogen in chickens, and efficient monitoring and control of this emerging zoonotic pathogen is urgently needed.
ISSN:2300-3235
2450-7393
2300-3235
2450-8608
DOI:10.1515/bvip-2015-0007