Immunoreactivity of S100β protein in the hippocampus of chinchilla

The aim of the study was to investigate S100β protein in astrocytes of CA1 and CA3 areas of the hippocampus proper and the dentate gyrus with the hilus yet undefined in mature males of chinchilla. The presence of S100β was determined using indirect immunohistochemical peroxidase-antiperoxidase metho...

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Bibliographic Details
Published in:Bulletin of the Veterinary Institute in Puławy 2014-01, Vol.58 (1), p.105-109
Main Authors: Krawczyk, Aleksandra, Rycerz, Karol, Szalak, Radosław, Jaworska-Adamu, Jadwiga
Format: Article
Language:English
Subjects:
Astrocytes
chinchilla
Dentate gyrus
Hippocampus
Immunoreactivity
Monoclonal antibodies
Neurogenesis
Peroxidase
Proteins
S100β protein
Stratum radiatum
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Summary:The aim of the study was to investigate S100β protein in astrocytes of CA1 and CA3 areas of the hippocampus proper and the dentate gyrus with the hilus yet undefined in mature males of chinchilla. The presence of S100β was determined using indirect immunohistochemical peroxidase-antiperoxidase method with specific monoclonal antibody against this protein. Most of the S100β-positive cells were detected in the subgranular zone of the dentate gyrus and in the middle part of the hilus. In CA3 area, it was found that the most numerous cells with S100β are in stratum radiatum. In CA1 area, there were single astrocytes expressing this protein. This data demonstrates species differences and a large quantity of S100β immunoreactive cells in the subgranular zone of the dentate gyrus of chinchilla, which may be associated with structural reorganisation of the hippocampus and with neurogenesis, learning, and memorising process dependent on the hippocampus.
ISSN:2300-3235
2450-7393
2300-3235
2450-8608
DOI:10.2478/bvip-2014-0017