Study on the properties of electrospun fiber for wound healing

• Published in: Journal of physics. Conference series 2021-06, Vol.1948 (1), p.12195
• Main Authors: Bo, Yuan, Xianyun, He, Tao, Zhang
• Format: Article
• Language: English
• Subjects: Atomic force microscopes; Atomic force microscopy; Bending machines; Biological properties; Crystal morphology; Diameters; Electrospinning; Mechanical properties; Modulus of elasticity; Physics; Polycaprolactone; Process parameters; Scale effect; Stress concentration; Surface structure; Tensile stress; Wound healing
• ISSN: 1742-6588; 1742-6596
• DOI: 10.1088/1742-6596/1948/1/012195

Electrospinning is a kind of technology which can efficiently prepare wound healing materials. In the application process of materials, it is very important to study the biological and mechanical properties of fiber materials. In this paper, Polycaprolactone fiber was prepared by controlling the process parameters of electrospinning process. The surface structure of the fiber was observed by scanning electron microscope and atomic force microscope. The results of electron microscope showed that there were cross stripes on the fiber surface, which would affect the mechanical properties of the fiber. The mechanical properties of fiber under two kinds of deformation conditions were measured by using high precision drawing equipment and self-made bending device. The experimental data show that the elastic modulus of the fiber under tensile load presents discrete distribution characteristics, and the elastic modulus of the fiber has nothing to do with the diameter; while in the bending experiment, the elastic modulus of the fiber increases significantly with the decrease of the fiber diameter, and the mechanical properties of the fiber show scale effect related to the fiber diameter. The reason for the different mechanical properties of the two groups of fibers may be related to the crystal morphology of the fiber surface and interior.