Synchronous Burkitt’s Lymphoma of Breast and Colon in a Female Patient: A Report of a Case and Review of Literature

Burkitt's lymphoma (BL) is a highly aggressive cancer of B-cells, which is more prevalent in African children. Extranodal involvement of the BL is not a common entity. Herein, we report a young woman who referred to University hospital due to rectorrhagia and breast swelling. Colonoscopy examin...

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Bibliographic Details
Published in:Türk onkoloji dergisi 2020, Vol.35 (4)
Main Author: jouybari, mohammad eslami
Format: Article
Language:English
Subjects:
Abdomen
Antigens
Bone marrow
Cancer
Case reports
Cell growth
Chemotherapy
Colon
Conflicts of interest
Consent
Epstein-Barr virus
HIV
Human immunodeficiency virus
Immunoglobulins
Infections
Lymphoma
Pain
Pediatrics
Ultrasonic imaging
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Summary:Burkitt's lymphoma (BL) is a highly aggressive cancer of B-cells, which is more prevalent in African children. Extranodal involvement of the BL is not a common entity. Herein, we report a young woman who referred to University hospital due to rectorrhagia and breast swelling. Colonoscopy examination revealed a large tumoral lesion of 5×6 cm with superficial ulceration in proximal of ascending colon. Computed tomography (CT) scan of the abdomen showed a 55×42 mm mass in ascending colon and caecum. No lymphadenopathy, splenomegaly and hepatomegaly were reported. Breast ultrasound was performed showed a 24×11 mm hypoechoic heterogeneous mass in the left breast. Bone marrow biopsy was normal. Immunohistochemical assay of colon and breast biopsies confirmed the diagnosis of primary BL. After four courses of chemotherapy, PET-CT revealed complete remission and no sign of metastasis. Since BL is a rapidly-growing neoplasm, prompt diagnosis and treatment can prevent unnecessary surgery and consequences of delay in treatment.
ISSN:1300-7467
2717-8978
DOI:10.5505/tjo.2020.2208