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Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia?
INTRODUCTION: Coronavirus disease 2019 (COVID-19)-related infections emerging from China that spread worldwide show a wide range of clinical courses from asymptomatic presentation to respiratory failure and even death. Similar to non-COVID-19 infections, obesity, age, and comorbidities can also affe...
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Published in: | Southern Clinics of Istanbul Eurasia 2021-01, Vol.31 (4), p.324-328 |
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description | INTRODUCTION: Coronavirus disease 2019 (COVID-19)-related infections emerging from China that spread worldwide show a wide range of clinical courses from asymptomatic presentation to respiratory failure and even death. Similar to non-COVID-19 infections, obesity, age, and comorbidities can also affect the clinical course of the disease. This study aimed to investigate the effect of obesity on the clinical course and mortality of patients hospitalized with COVID-19 pneumonia. METHODS: Between March 11 and April 30, 2020, patients hospitalized with COVID-19 pneumonia were retrospectively analyzed. Patients were classified as having severe and mild disease based on oxygen, non-invasive mechanical ventilation (NIMV), and invasive (IMV) mechanical ventilation requirements. Two groups were evaluated based on body mass index (BMI) of ≥25 and ≥30 kg/m2. RESULTS: Of the 125 patients, 82 (65.6%) were men, and their mean age was 51.77±4.99 years. Their mean BMI was 27.76±4.76 kg/m2. The difference of the mean BMI between the patients with severe and mild disease was statistically significant (28.8±5.36 and 26.9±4.10, respectively) (p=0.028). BMI of ≥25 and ≥30 kg/m2 were noted in 43.4% and 20.8% of patients with severe and mild disease, respectively, which was statistically significant (p=0.007). Moreover, 70.6% of 17 patients older than 65 years with BMI of ≥25 kg/m2 had a severe clinical course (p=0.021). Among patients requiring NIMV, 59.1% and 31.8% had a BMI of ≥25 and 30 kg/m2, respectively. Among patients requiring IMV, 66.7% and 37.5% had a BMI of ≥25 and 30 kg/m2, respectively. No statistically significant difference was found between BMI and NIMV and IMV need. Death occurred in 14.8% of the patients. No statistically significant difference was found between the BMI of those who died and survived (p=0.768). DISCUSSION AND CONCLUSION: Bu kohort çalışması, aşırı kilo ve obezitenin hastalık şiddetini değerlendirmede ve tahminde önemli bir faktör olduğunu ve özellikle VKİ ≥30 kg/m2 olan hastaların takiplerinde dikkatli olunması gerektiğini göstermiştir. |
doi_str_mv | 10.14744/scie.2020.29974 |
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Similar to non-COVID-19 infections, obesity, age, and comorbidities can also affect the clinical course of the disease. This study aimed to investigate the effect of obesity on the clinical course and mortality of patients hospitalized with COVID-19 pneumonia. METHODS: Between March 11 and April 30, 2020, patients hospitalized with COVID-19 pneumonia were retrospectively analyzed. Patients were classified as having severe and mild disease based on oxygen, non-invasive mechanical ventilation (NIMV), and invasive (IMV) mechanical ventilation requirements. Two groups were evaluated based on body mass index (BMI) of ≥25 and ≥30 kg/m2. RESULTS: Of the 125 patients, 82 (65.6%) were men, and their mean age was 51.77±4.99 years. Their mean BMI was 27.76±4.76 kg/m2. The difference of the mean BMI between the patients with severe and mild disease was statistically significant (28.8±5.36 and 26.9±4.10, respectively) (p=0.028). BMI of ≥25 and ≥30 kg/m2 were noted in 43.4% and 20.8% of patients with severe and mild disease, respectively, which was statistically significant (p=0.007). Moreover, 70.6% of 17 patients older than 65 years with BMI of ≥25 kg/m2 had a severe clinical course (p=0.021). Among patients requiring NIMV, 59.1% and 31.8% had a BMI of ≥25 and 30 kg/m2, respectively. Among patients requiring IMV, 66.7% and 37.5% had a BMI of ≥25 and 30 kg/m2, respectively. No statistically significant difference was found between BMI and NIMV and IMV need. Death occurred in 14.8% of the patients. No statistically significant difference was found between the BMI of those who died and survived (p=0.768). DISCUSSION AND CONCLUSION: Bu kohort çalışması, aşırı kilo ve obezitenin hastalık şiddetini değerlendirmede ve tahminde önemli bir faktör olduğunu ve özellikle VKİ ≥30 kg/m2 olan hastaların takiplerinde dikkatli olunması gerektiğini göstermiştir.</description><identifier>ISSN: 2587-0998</identifier><identifier>EISSN: 2587-1404</identifier><identifier>EISSN: 2587-0998</identifier><identifier>DOI: 10.14744/scie.2020.29974</identifier><language>eng</language><publisher>Istanbul: Kare Publishing</publisher><subject>Body mass index ; Coronaviruses ; COVID-19 ; covid-19; pneumonia; severe disease ; Pneumonia ; Respiratory failure ; Ventilation</subject><ispartof>Southern Clinics of Istanbul Eurasia, 2021-01, Vol.31 (4), p.324-328</ispartof><rights>2020. This work is published under https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2546656762?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,27924,27925,38516,43895</link.rule.ids><linktorsrc>$$Uhttps://www.proquest.com/docview/2546656762?pq-origsite=primo$$EView_record_in_ProQuest$$FView_record_in_$$GProQuest$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Turan, Demet</creatorcontrib><creatorcontrib>Tanrıverdi, Elif</creatorcontrib><creatorcontrib>Çörtük, Mustafa</creatorcontrib><creatorcontrib>Binnaz Zeynep Yıldırım</creatorcontrib><creatorcontrib>Efsun Gonca Uğur Chousein</creatorcontrib><creatorcontrib>Çınarka, Halit</creatorcontrib><creatorcontrib>Özgul, Mehmet Akif</creatorcontrib><creatorcontrib>Çetinkaya, Erdoğan</creatorcontrib><title>Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia?</title><title>Southern Clinics of Istanbul Eurasia</title><description>INTRODUCTION: Coronavirus disease 2019 (COVID-19)-related infections emerging from China that spread worldwide show a wide range of clinical courses from asymptomatic presentation to respiratory failure and even death. Similar to non-COVID-19 infections, obesity, age, and comorbidities can also affect the clinical course of the disease. This study aimed to investigate the effect of obesity on the clinical course and mortality of patients hospitalized with COVID-19 pneumonia. METHODS: Between March 11 and April 30, 2020, patients hospitalized with COVID-19 pneumonia were retrospectively analyzed. Patients were classified as having severe and mild disease based on oxygen, non-invasive mechanical ventilation (NIMV), and invasive (IMV) mechanical ventilation requirements. Two groups were evaluated based on body mass index (BMI) of ≥25 and ≥30 kg/m2. RESULTS: Of the 125 patients, 82 (65.6%) were men, and their mean age was 51.77±4.99 years. Their mean BMI was 27.76±4.76 kg/m2. The difference of the mean BMI between the patients with severe and mild disease was statistically significant (28.8±5.36 and 26.9±4.10, respectively) (p=0.028). BMI of ≥25 and ≥30 kg/m2 were noted in 43.4% and 20.8% of patients with severe and mild disease, respectively, which was statistically significant (p=0.007). Moreover, 70.6% of 17 patients older than 65 years with BMI of ≥25 kg/m2 had a severe clinical course (p=0.021). Among patients requiring NIMV, 59.1% and 31.8% had a BMI of ≥25 and 30 kg/m2, respectively. Among patients requiring IMV, 66.7% and 37.5% had a BMI of ≥25 and 30 kg/m2, respectively. No statistically significant difference was found between BMI and NIMV and IMV need. Death occurred in 14.8% of the patients. No statistically significant difference was found between the BMI of those who died and survived (p=0.768). DISCUSSION AND CONCLUSION: Bu kohort çalışması, aşırı kilo ve obezitenin hastalık şiddetini değerlendirmede ve tahminde önemli bir faktör olduğunu ve özellikle VKİ ≥30 kg/m2 olan hastaların takiplerinde dikkatli olunması gerektiğini göstermiştir.</description><subject>Body mass index</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>covid-19; pneumonia; severe disease</subject><subject>Pneumonia</subject><subject>Respiratory failure</subject><subject>Ventilation</subject><issn>2587-0998</issn><issn>2587-1404</issn><issn>2587-0998</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>COVID</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNotkE1Lw0AYhIMoWGrvHhc8p-73Zk9So9VAxSK9h81-2K1ptu4mav-9wXqal2F4eGey7BrBOaKC0tukvZ1jiOEcSynoWTbBrBA5opCe_99QyuIym6W0g3AMQswgn2RtlcB9MEfwolICVWfsD1iAN58-wFLpPkTgO9BvLShb33mtWlCGISYLggNr1Xvb9Ql8-347-jF06svHIYEHn6waQxgiCdadHfah8-ruKrtwqk129q_TbLN83JTP-er1qSoXq9xIivMGU4qRaRpoKLHSMIEFstQa6xBjrCC8QUIwSFVhGqqwY0hAAo3TCErYKDLNqhPWBLWrD9HvVTzWQfn6zwjxvVax97q1tcZFwxHXThaaWueUKCxyCJFxS-IIGlk3J9Yhhs_Bpr7ejf278fsaM8o544Jj8gtqWXJf</recordid><startdate>20210101</startdate><enddate>20210101</enddate><creator>Turan, Demet</creator><creator>Tanrıverdi, Elif</creator><creator>Çörtük, Mustafa</creator><creator>Binnaz Zeynep Yıldırım</creator><creator>Efsun Gonca Uğur Chousein</creator><creator>Çınarka, Halit</creator><creator>Özgul, Mehmet Akif</creator><creator>Çetinkaya, Erdoğan</creator><general>Kare Publishing</general><general>KARE Publishing</general><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>DOA</scope></search><sort><creationdate>20210101</creationdate><title>Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia?</title><author>Turan, Demet ; Tanrıverdi, Elif ; Çörtük, Mustafa ; Binnaz Zeynep Yıldırım ; Efsun Gonca Uğur Chousein ; Çınarka, Halit ; Özgul, Mehmet Akif ; Çetinkaya, Erdoğan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-d942-b24421dbb0d43e9d57271e4edef1555836b177504a8db4a2f517030dfc1090ba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Body mass index</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>covid-19; pneumonia; severe disease</topic><topic>Pneumonia</topic><topic>Respiratory failure</topic><topic>Ventilation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Turan, Demet</creatorcontrib><creatorcontrib>Tanrıverdi, Elif</creatorcontrib><creatorcontrib>Çörtük, Mustafa</creatorcontrib><creatorcontrib>Binnaz Zeynep Yıldırım</creatorcontrib><creatorcontrib>Efsun Gonca Uğur Chousein</creatorcontrib><creatorcontrib>Çınarka, Halit</creatorcontrib><creatorcontrib>Özgul, Mehmet Akif</creatorcontrib><creatorcontrib>Çetinkaya, Erdoğan</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Directory of Open Access Journals</collection><jtitle>Southern Clinics of Istanbul Eurasia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Turan, Demet</au><au>Tanrıverdi, Elif</au><au>Çörtük, Mustafa</au><au>Binnaz Zeynep Yıldırım</au><au>Efsun Gonca Uğur Chousein</au><au>Çınarka, Halit</au><au>Özgul, Mehmet Akif</au><au>Çetinkaya, Erdoğan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia?</atitle><jtitle>Southern Clinics of Istanbul Eurasia</jtitle><date>2021-01-01</date><risdate>2021</risdate><volume>31</volume><issue>4</issue><spage>324</spage><epage>328</epage><pages>324-328</pages><issn>2587-0998</issn><eissn>2587-1404</eissn><eissn>2587-0998</eissn><abstract>INTRODUCTION: Coronavirus disease 2019 (COVID-19)-related infections emerging from China that spread worldwide show a wide range of clinical courses from asymptomatic presentation to respiratory failure and even death. Similar to non-COVID-19 infections, obesity, age, and comorbidities can also affect the clinical course of the disease. This study aimed to investigate the effect of obesity on the clinical course and mortality of patients hospitalized with COVID-19 pneumonia. METHODS: Between March 11 and April 30, 2020, patients hospitalized with COVID-19 pneumonia were retrospectively analyzed. Patients were classified as having severe and mild disease based on oxygen, non-invasive mechanical ventilation (NIMV), and invasive (IMV) mechanical ventilation requirements. Two groups were evaluated based on body mass index (BMI) of ≥25 and ≥30 kg/m2. RESULTS: Of the 125 patients, 82 (65.6%) were men, and their mean age was 51.77±4.99 years. Their mean BMI was 27.76±4.76 kg/m2. The difference of the mean BMI between the patients with severe and mild disease was statistically significant (28.8±5.36 and 26.9±4.10, respectively) (p=0.028). BMI of ≥25 and ≥30 kg/m2 were noted in 43.4% and 20.8% of patients with severe and mild disease, respectively, which was statistically significant (p=0.007). Moreover, 70.6% of 17 patients older than 65 years with BMI of ≥25 kg/m2 had a severe clinical course (p=0.021). Among patients requiring NIMV, 59.1% and 31.8% had a BMI of ≥25 and 30 kg/m2, respectively. Among patients requiring IMV, 66.7% and 37.5% had a BMI of ≥25 and 30 kg/m2, respectively. No statistically significant difference was found between BMI and NIMV and IMV need. Death occurred in 14.8% of the patients. No statistically significant difference was found between the BMI of those who died and survived (p=0.768). DISCUSSION AND CONCLUSION: Bu kohort çalışması, aşırı kilo ve obezitenin hastalık şiddetini değerlendirmede ve tahminde önemli bir faktör olduğunu ve özellikle VKİ ≥30 kg/m2 olan hastaların takiplerinde dikkatli olunması gerektiğini göstermiştir.</abstract><cop>Istanbul</cop><pub>Kare Publishing</pub><doi>10.14744/scie.2020.29974</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Body mass index Coronaviruses COVID-19 covid-19 pneumonia severe disease Pneumonia Respiratory failure Ventilation |
title | Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia? |
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