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Extremely Sensitive Photonic Crystal Fiber–Based Cancer Cell Detector in the Terahertz Regime
A new photonic crystal fiber (PCF)–based, hollow-core, optical waveguide is proposed and numerically investigated to quickly identify numerous species of cancerous cells in the human body. Typical and cancerous cells have different refractive indices (RIs), and via this characteristic, the other imp...
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Published in: | Plasmonics (Norwell, Mass.) Mass.), 2021, Vol.16 (4), p.1297-1306 |
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creator | Habib, Ahasan Rashed, Ahmed Nabih Zaki El-Hageen, Hazem M. Alatwi, Aadel M. |
description | A new photonic crystal fiber (PCF)–based, hollow-core, optical waveguide is proposed and numerically investigated to quickly identify numerous species of cancerous cells in the human body. Typical and cancerous cells have different refractive indices (RIs), and via this characteristic, the other important optical parameters are evaluated. The guiding properties of this proposed cancer cell sensor are analyzed in the COMSOL Multiphysics environment which used the finite element method as mathematical tool to solve differential equations. Furthermore, to ensure the highest simulation accuracy, extremely fine mesh elements are introduced. The simulation studies confirm that the proposed sensor, at 2.5 THz, achieves an extremely high relative sensitivity of almost 98% with negligible loss ( |
doi_str_mv | 10.1007/s11468-021-01409-6 |
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Typical and cancerous cells have different refractive indices (RIs), and via this characteristic, the other important optical parameters are evaluated. The guiding properties of this proposed cancer cell sensor are analyzed in the COMSOL Multiphysics environment which used the finite element method as mathematical tool to solve differential equations. Furthermore, to ensure the highest simulation accuracy, extremely fine mesh elements are introduced. The simulation studies confirm that the proposed sensor, at 2.5 THz, achieves an extremely high relative sensitivity of almost 98% with negligible loss (< 0.025 dB/cm). Furthermore, a high numerical aperture (NA) and spot size, with low modal area, enhance the propagation characteristics of the sensor to a new height. The sensor’s physical structure is very simple so that it can be easily fabricated with modern fabrication technology. 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subjects | Biochemistry Biological and Medical Physics Biophysics Biotechnology Cancer Chemistry Chemistry and Materials Science Crystal fibers Differential equations Finite element method Nanotechnology Numerical aperture Optical properties Optical waveguides Photonic crystals Refractivity Sensors |
title | Extremely Sensitive Photonic Crystal Fiber–Based Cancer Cell Detector in the Terahertz Regime |
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