Alopecia totalis following hand-foot-and-mouth disease

We present a case of a 13-month-old male patient with alopecia totalis that began two months after an episode of hand-foot-and-mouth disease. It is hypothesized that the viral infection triggered an autoimmune response, which lead to production of lymphocytes targeting an antigen present in the hair...

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Bibliographic Details
Published in:Pediatric dermatology 2021-05, Vol.38 (3), p.640-642
Main Authors: Oska, Sandra, Bedford, Lisa M, Potts, Geoffrey A
Format: Article
Language:English
Subjects:
Alopecia
Baldness
Case reports
Dermatology
Hand-foot-and-mouth disease
Lymphocytes
Pediatrics
Viral infections
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Summary:We present a case of a 13-month-old male patient with alopecia totalis that began two months after an episode of hand-foot-and-mouth disease. It is hypothesized that the viral infection triggered an autoimmune response, which lead to production of lymphocytes targeting an antigen present in the hair bulb. Future research is necessary to determine whether and how the pathophysiology of alopecia totalis may be triggered by viral infection.
ISSN:0736-8046
1525-1470
DOI:10.1111/pde.14550