Multiple myeloma mimicking metastatic lung cancer

Multiple myeloma is a hematological malignancy characterized by a clonal proliferation of plasma cells in the bone marrow. Extramedullary dissemination of multiple myeloma is uncommon. Only in rare cases, the malignant plasma cells of multiple myeloma had infiltrated the lung parenchyma. In this cas...

Full description

Saved in:
Bibliographic Details
Published in:Türk onkoloji dergisi 2015, Vol.30 (3)
Main Author: FURUNCUOGLU, Yavuz
Format: Article
Language:English
Subjects:
Biopsy
Blood
Blood diseases
Bone marrow
Case reports
Hematology
Internal medicine
Lung cancer
Medical diagnosis
Medicine
Mesothelioma
Metabolism
Metastasis
Multiple myeloma
Outpatient care facilities
Pain
Patients
Plasma
Pleural effusion
Tumors
University faculty
Vertebrae
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Multiple myeloma is a hematological malignancy characterized by a clonal proliferation of plasma cells in the bone marrow. Extramedullary dissemination of multiple myeloma is uncommon. Only in rare cases, the malignant plasma cells of multiple myeloma had infiltrated the lung parenchyma. In this case report, we presented a case of multiple myeloma with lung plasmacytoma, in a 42-year-old patient, hospitalized for pain and infiltrative mass in the right lung. The results of his initial evaluation with computed tomography and positron emission tomograpy scanning, resembled lung tumor with bone metastasis. Surprisingly, biopsies from lung tumor and bone metastasis, revealed malignant plasma cells. We found M spike in protein electrophoresis and lambda monoclonal band in immune electrophoresis. A bone marrow biopsy evaluation was done and justified multiple myeloma diagnosis before hematology referral. Multiple myeloma diagnosis at the age of 42 is quite rare.
ISSN:1300-7467
2717-8978
DOI:10.5505/tjoncol.2015.1254