A portable optical fiber biosensor for the detection of zearalenone based on the localized surface plasmon resonance

•A portable optical fiber-based LSPR biosensor was successfully developed to determine the concentration of ZEN.•This tip LSPR biosensor could be regenerated by simple cutting and polishing the end of the used facet of optical fiber.•Key factors, the distribution of gold nanoparticles, pH and densit...

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Bibliographic Details
Published in:Sensors and actuators. B, Chemical Chemical, 2021-06, Vol.336, p.129752, Article 129752
Main Authors: Xu, Yichao, Xiong, Meng, Yan, Hui
Format: Article
Language:English
Subjects:
Aptamer
Biosensor
Biosensors
Continuous improvement
Food
Gold
Localized surface plasmon resonance
Nanoparticles
Nucleic acids
Optical fiber
Optical fibers
Selectivity
Surface plasmon resonance
Zearalenone
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Summary:•A portable optical fiber-based LSPR biosensor was successfully developed to determine the concentration of ZEN.•This tip LSPR biosensor could be regenerated by simple cutting and polishing the end of the used facet of optical fiber.•Key factors, the distribution of gold nanoparticles, pH and density of ZEN aptamer, were optimized in the LSPR biosensor.•This LSPR biosensor displayed an excellent ZEN detection performance in real sample. With the continuous improvement of people's living standards, food safety issues have gradually become one of the main concerns. Rapid and accurate detection of zearalenone (ZEN) in food has attracted broad research interest. In this work, a low-cost, portable, and reusable optical fiber-based localized surface plasmon resonance (LSPR) biosensor for ZEN was developed. Gold nanoparticles around 25 nm were synthesized and coated on the cross-section of the end of an optical fiber, and then the ZEN nucleic acid aptamer was modified to form the LSPR biosensor for ZEN detection. Results showed that there was a good relationship between ZEN concentrations and the redshifts of LSPR peak in the range of 1 ∼ 480 ng/mL, the limit of detection was 0.102 ng/mL. Moreover, the sensing interface could be easily regenerated by cutting and polishing the end of the optical fiber, indicating that the LSPR biosensor was reusable. It also has exceptional high selectivity for ZEN and good recovery and repeatability, which has a good prospect for the on-site ZEN monitoring.
ISSN:0925-4005
1873-3077
DOI:10.1016/j.snb.2021.129752