Bartonella henselae infection in the pediatric solid organ transplant recipient

Bartonella henselae infection can cause a wide spectrum of diseases in both the immunocompetent and immunocompromised host with BA a severe form relegated to immunocompromised hosts, including solid organ transplant population. There are established criteria for diagnosis of Bartonella infection bas...

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Bibliographic Details
Published in:Pediatric transplantation 2021-08, Vol.25 (5), p.e13823-n/a
Main Authors: Lopez, Santiago Manuel Cayetano, Davis, Amy, Zinn, Matthew, Feingold, Brian, Green, Michael, Michaels, Marian G.
Format: Article
Language:English
Subjects:
Animals
Anti-Bacterial Agents - therapeutic use
Azithromycin - therapeutic use
Bartonella henselae
bartonella infection
Cat-Scratch Disease - diagnosis
Cat-Scratch Disease - drug therapy
Cat-Scratch Disease - immunology
Cats
Child
Diagnosis
Heart Transplantation
Humans
Immunocompromised Host
Immunocompromised hosts
Infections
Literature reviews
pediatric solid organ transplantation
Pediatrics
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Summary:Bartonella henselae infection can cause a wide spectrum of diseases in both the immunocompetent and immunocompromised host with BA a severe form relegated to immunocompromised hosts, including solid organ transplant population. There are established criteria for diagnosis of Bartonella infection based on clinical presentation, serologic testing, imaging studies and, when indicated, tissue sampling for histopathological evaluation, particularly for BA. However, treatment recommendations for BA are inconclusive. Furthermore, there are no studies in the pediatric solid organ transplant population for antimicrobial therapy during BA secondary to Bartonella henselae infection. A case of BA following heart transplant is presented along with a literature review of clinical presentation; diagnosis and therapy for BA in the pediatric solid organ transplant population.
ISSN:1397-3142
1399-3046
DOI:10.1111/petr.13823