Isolation and Identification of Active Compounds from Papaya Plants and Activities as Antimicrobial

Extraction and isolation of papaya seeds and leaves (Carica papaya L) has been performed using n-hexane and ethanol solvents. Further isolation of the extract obtained using ethyl acetate and diethyl ether solvents. The result of the phytochemical test of papaya extract obtained by mixture of an act...

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Bibliographic Details
Published in:IOP conference series. Materials Science and Engineering 2018-04, Vol.349 (1), p.12007
Main Authors: Prasetya, A T, Mursiti, S, Maryan, S, Jati, N K
Format: Article
Language:English
Subjects:
Alkaloids
Diethyl ether
Ethanol
Ethyl acetate
Flavonoids
Fungicides
Hexanes
Papayas
Saponins
Seeds
Solvents
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Summary:Extraction and isolation of papaya seeds and leaves (Carica papaya L) has been performed using n-hexane and ethanol solvents. Further isolation of the extract obtained using ethyl acetate and diethyl ether solvents. The result of the phytochemical test of papaya extract obtained by mixture of an active compound of flavonoids, alkaloids, tannins, steroids, and saponins. Ethyl acetate isolates containing only flavonoids and diethyl ether isolates contain only alkaloids. Extracts and isolates from papaya plants had gram-positive antibacterial activity greater than the gram-negative bacteria, but both did not have antifungal activity. Papaya extracts have greater antibacterial activity than flavonoid isolates and alkaloid isolates. Strong antibacterial inhibitory sequences are extracts of papaya plants, flavonoid isolates, and alkaloid isolates.
ISSN:1757-8981
1757-899X
DOI:10.1088/1757-899X/349/1/012007