TCT-690 Incremental Age-related 1-year MACCE after Acute Myocardial Infarction in the drug-eluting stent era (from KAMIR-NIH registry)

• Published in: Journal of the American College of Cardiology 2018-09, Vol.72 (13), p.B275-B276
• Main Authors: Kim, Dae-Won, Kim, Dong-Bin, Hong, Keepyung, Kim, Sung-Mi, Kim, Kyun Young, Her, Sung-Ho, Park, Hawook, Kim, Jee Hyuk, Lee, Myun Hee, Bu, SeongHyeon, Hwang, Byung-Hee
• Format: Article
• Language: English
• Subjects: Age; Cardiology; Drug delivery; Electrocardiography; Heart attacks; Implants; Myocardial infarction; Stents; Surgical implants
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/j.jacc.2018.08.1904

Background We evaluated the age-related 1-year major adverse cardiocerebrovascular events (MACCE) after percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI). Patients were analyzed for 1-year composite of MACCE (cardiac death, myocardial infarction, target vessel revascularization, cerebrovascular events) after AMIResults After adjustment for confounding parameters, the analysis results showed that patients with AMI had incremental risk of 1-year MACCE (Group II ; aHR = 1.224, 95% CI 0.965-1.525, p = 0.096, Group III ; aHR = 1.316, 95% CI 1.037-1.671, p = 0.024, Group IV ; aHR = 1.975, 95% CI 1.500-62.601, p < 0.001) compared to Group I. Especially, cardiac death in the composite of primary end point played a major role in this effect (Group II ; aHR = 1.335, 95% CI 0.941-1.895, p = 0.106, Group III ; aHR = 1.575, 95% CI 1.122-2.210, p = 0.009, Group IV ; aHR = 2.803, 95% CI 1.937-4.054, p < 0.001). Group p-value Log-rank p-value HR 95.0% CI p-value Adjusted HR 95.0% CI p-value Lower Upper Lower Upper 1-year Primary end-point