The Applying of Yeast Saccharomyces Cerevisiae for Rapid Estimation of Surface-Active Substances' Toxicity

To assess the toxicity of several surface-active substances the foaming activity of the yeast Saccharomyces cerevisiae is proposed to use as biotest. The criterion of toxicity in this test was the suppression of foaming in the suspension of yeast with glucose. The proposed test reaction showed a hig...

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Bibliographic Details
Published in:IOP conference series. Earth and environmental science 2019-06, Vol.272 (3), p.32208
Main Authors: Vyatchina, O F, Zhdanova, G O, Xie, Beizhen, Ponomareva, A L, Stom, D I, Fialkow, V A, Kupchinsky, A B, Saksonov, M N
Format: Article
Language:English
Subjects:
Foaming
Survival
Toxicity
Toxicity testing
Yeast
Yeasts
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Summary:To assess the toxicity of several surface-active substances the foaming activity of the yeast Saccharomyces cerevisiae is proposed to use as biotest. The criterion of toxicity in this test was the suppression of foaming in the suspension of yeast with glucose. The proposed test reaction showed a higher sensitivity to surface-active substances compared with the survival rate and the growth function of yeast. The results of the toxicologic testing are collated with data obtained using conventional techniques. The benefits of a new test reaction are technical simplicity, rate, low material costs, lack of need for constant maintenance in the active state of the test-culture, good reproducibility.
ISSN:1755-1307
1755-1315
DOI:10.1088/1755-1315/272/3/032208