Antioxidant Activity of Haramounting Leaf Ethanol Extract (Rhodomytrus tomentosa) In Preventing Heart Damage of Mice (Mus musculus L.) after exposure to Electronic Cigarette

Cigarette smoke is one factor that increases free radicals in the blood will affect liver health in the body. The purpose of this study is to find outthe effect of giving leaves ethanol extract haramounting to histology of male mice liver exposed to electric cigarettes. The design of this study used...

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Bibliographic Details
Published in:IOP conference series. Earth and environmental science 2019-07, Vol.305 (1), p.12080
Main Authors: Ilyas, S, Tanjung, R S, Hutahaean, S, Tanjung, M, Elimasni, Jamilah, I, Murdela, F
Format: Article
Language:English
Subjects:
Antioxidants
Body weight
Cigarette smoke
Cigarettes
Damage prevention
Electronic cigarettes
Ethanol
Exposure
Free radicals
Hepatocytes
Histology
Leaves
Liver
Paraffin
Paraffins
Smoke
Smoking
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Summary:Cigarette smoke is one factor that increases free radicals in the blood will affect liver health in the body. The purpose of this study is to find outthe effect of giving leaves ethanol extract haramounting to histology of male mice liver exposed to electric cigarettes. The design of this study used Completely Randomized Design (CRD) consisting of + Group, - Group and three treatments of Haramounting Leaf Ethanol Extract (Rhodomyrtus tomentosa (Aiton) Hassk.) for 30 days at a dose of 100 mg/kg BW Body Weight, 200 mg/kg BW and 300 mg/kg BW for treament use of five replications. Liver organ preparations were made using paraffin block method and Hematoxylin Erlich-Eosin (HE) staining. The results of the study show on histological observations The liver has a tendency that electric cigarette smoke can cause damage in liver cells. The results of this study indicate that ethanol extract leaves of Haramounting after exposure to eletric cigarette smoke can effectively regenerate damaged liver cells.
ISSN:1755-1307
1755-1315
DOI:10.1088/1755-1315/305/1/012080