Dentigerous cyst exhibiting prominent mucous cell metaplasia: report of a unique case mimicking central mucoepidermoid carcinoma

A Japanese male aged 61 presented with persistent pain in the left posterior area of the mandible for several weeks. A panoramic X-ray revealed a unilocular lesion showing characteristics of a dentigerous cyst associated with an impacted third molar. A cystectomy was performed and histopathological...

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Bibliographic Details
Published in:Medical molecular morphology 2021-09, Vol.54 (3), p.253-258
Main Authors: Harada, Hiroshi, Kihara, Toshiyuki, Abe, Hideyuki, Kawahara, Akihiko, Akiba, Jun, Kurose, Akira
Format: Article
Language:English
Subjects:
Anatomy
Asians
Carcinoma, Mucoepidermoid
Case Report
Cysts
Dentigerous Cyst - diagnosis
Dentigerous Cyst - surgery
Goblet Cells - pathology
Humans
Lesions
Male
Mandible
Medicine
Medicine & Public Health
Metaplasia
Middle Aged
Mimicry
Molecular Medicine
Mucins - analysis
Odontogenic Cysts - diagnosis
Odontogenic Cysts - surgery
Pathology
Squamous cells
Trans-Activators
Citations: Items that this one cites
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Summary:A Japanese male aged 61 presented with persistent pain in the left posterior area of the mandible for several weeks. A panoramic X-ray revealed a unilocular lesion showing characteristics of a dentigerous cyst associated with an impacted third molar. A cystectomy was performed and histopathological examination revealed a cystic lesion with a fibrous wall. The lumen was covered with non-keratinizing squamous cells with obvious intercellular bridges, which were intermingled with partially ciliated goblet-cell-type mucous and columnar cells. Such cystic lesions should be carefully examined to distinguish them from the glandular odontogenic cyst and central mucoepidermoid carcinoma of the jawbone.
ISSN:1860-1480
1860-1499
DOI:10.1007/s00795-020-00278-y