Chronomodulated Pulsatile Therapeutic System of Lisinopril for Blood Pressure on Early Morning Surge - Design and Quantification

The IR spectra of the test samples were obtained by pressed pellet technique using potassium bromide and the ratio of sample is 1:100[4] Methods: Formulation of immediate release granules in pulsatile device Lisinopril immediate release granules (IMR) were made by wet granulation method. [...]talc a...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences and research 2021-07, Vol.13 (7), p.374-380
Main Authors: Rajaram, Subashini, Rajan, D Senthil, Jose, Aleena
Format: Article
Language:English
Subjects:
Asthma
Cellulose
Drug delivery systems
Hypertension
Polymers
Rhinitis
Sodium
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Summary:The IR spectra of the test samples were obtained by pressed pellet technique using potassium bromide and the ratio of sample is 1:100[4] Methods: Formulation of immediate release granules in pulsatile device Lisinopril immediate release granules (IMR) were made by wet granulation method. [...]talc and magnesium stearate was added to enhance the flow property of granules. According to USP, capsule size "1" can accommodate total weight of 500 mg. [...]the filled capsules were sealed with the help of capsule hand filling machine [6,7].
ISSN:0975-1459