Effect of Rice Bran Oil on Lipid Accumulation in Normal Rats

• Published in: Annals of nutrition and metabolism 2019-01, Vol.75, p.250
• Main Authors: Navratilova, Hana Fitria, Fitriyana, Intan Nur, Damayanthi, Evy, Soejoedono, Retno Damayanti
• Format: Article
• Language: English
• Subjects: Accumulation; Adipose tissue; Body fat; Laboratory animals; Lipids; Lipolysis; Nutrition; Nutrition research; Oils & fats; Rice; Rice bran oil; Weight
• ISSN: 0250-6807; 1421-9697
• DOI: 10.1159/000501751

Background: Rice Bran Oil (RBO) contains gamma-oryzanol which demonstrated a hypolipidemic effect of RBO on experimental rat. Methods: We tested whether RBO would also has an effect on decreasing abdominal adipose tissue weight and size by inducing lipolysis. Twenty-one normal male rats at sevenweekold were fed a control diet and divided into a control group, a standard group (Orlistat 10.8 mg/kg bw/day), and a treatment group (RBO contain 57.6 mg oryzanol/day). The treatment was for 28 days. Results: There was no significant difference in growth performance (p > 0.05) and feed intake (p > 0.05) between groups. Treatment of RBO result in lower adipose tissue weight (1.23 ± 0.24 g) compared to control (1.41 ± 0.18 g). Moreover, RBO group has lowest mesenteric fat percentage (0.24 ± 0.05%) among groups (control = 0.34 ± 0.08%; standard = 0.28 ± 0.14%) but not statistically different (p > 0.05). In addition, there was no significant difference in adipose tissue size for all groups (p > 0.05). Conclusion: These results suggested that consumption of RBO in normal physiology state will not lead to lipid accumulation. However the effect on inducing lipolysis is still not confirmed.