Synthesis of Biogenic Silver Nanoparticles with Eco-Friendly Processes Using Ganoderma lucidum Extract and Evaluation of Their Theranostic Applications

The green synthesis of silver nanoparticles (AgNPs) using plant extract, the cost-effective solution, and the abundance and environmental issue have been gaining much attention to scientists. Ganoderma lucidum (GL) commonly known as Lingzhi in Chinese and Reishi in Japanese, with a proven anticancer...

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Bibliographic Details
Published in:Journal of nanomaterials 2021, Vol.2021, p.1-11
Main Authors: Nguyen, Vinh Phu, Le Trung, Hieu, Nguyen, Thu Huong, Hoang, DongQuy, Tran, Thai Hoa
Format: Article
Language:English
Subjects:
Breast cancer
Buffer zones
Cancer therapies
Cell growth
Cytotoxicity
Ethanol
Liver cancer
Methods
Mushrooms
Nanomaterials
Nanoparticles
National parks
Optical properties
Penicillin
Reaction time
Silver
Spectrum analysis
Synthesis
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Summary:The green synthesis of silver nanoparticles (AgNPs) using plant extract, the cost-effective solution, and the abundance and environmental issue have been gaining much attention to scientists. Ganoderma lucidum (GL) commonly known as Lingzhi in Chinese and Reishi in Japanese, with a proven anticancer benefit, is discovered in the buffer zone of Bach Ma National Park, Nam Dong district, Thua Thien Hue province. In this work, the AgNPs were synthesized in a simple and effective biochemical reduction process using GL which is one of the biological organisms, as a reducing and stable agent. The optimum conditions of various experimental parameters such as pH, reaction time, concentration, and temperature were investigated. Obtained AgNPs were characterized by UV-Vis, FTIR, SEM, energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and transmission electron microscopy (TEM). The effects of AgNP/GL materials and GL aqueous extraction on the antiproliferative activities of HepG2 and MCF-7 cells were studied. The novel AgNP/GL-based multicomponent suspension is a key compound that could find a good application in the medical and pharmaceutical sciences.
ISSN:1687-4110
1687-4129
DOI:10.1155/2021/6135920