The role of nutrition in the treatment of sarcopenia in Parkinson's disease: a scoping review

In a randomised controlled trial (RCT)(3), participants consumed a protein, leucine and vitamin D supplement alongside a four-week physical activity intervention, or a placebo with no exercise (n = 150 PwP). A second RCT(4), in inpatient older adults (n = 127; n = 8 PwP [6.3%]), investigated twice-d...

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Bibliographic Details
Published in:Proceedings of the Nutrition Society 2021, Vol.80 (OCE3), Article E131
Main Authors: Brazier, D., Breasail, M. Ó., Lithander, F.E., Henderson, E.J.
Format: Article
Language:English
Subjects:
Adults
Dietary supplements
Exercise
Gait
Intervention
Leucine
Movement disorders
Neurodegenerative diseases
Nutrition
Older people
Parkinson's disease
Physical activity
Physical fitness
Placebos
Proteins
Rehabilitation
Sarcopenia
Vitamin D
Whey
Whey protein
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Summary:In a randomised controlled trial (RCT)(3), participants consumed a protein, leucine and vitamin D supplement alongside a four-week physical activity intervention, or a placebo with no exercise (n = 150 PwP). A second RCT(4), in inpatient older adults (n = 127; n = 8 PwP [6.3%]), investigated twice-daily whey protein supplementation (40g/d) in addition to physical rehabilitation programme lasting between four and eight weeks, and reported significant improvements in gait speed on discharge (mean difference, +0.062 m/s/month [95%CI, 0.043 to 0.082])(4). In older adults, there is an abundance of evidence positively supporting nutritional strategies which, alone or in combination with physical activity interventions, can slow progression of sarcopenia.
ISSN:0029-6651
1475-2719
DOI:10.1017/S0029665121002548