Physiological 2-deoxy-2-[fluorine-18] fluoro-D-glucose accumulation in the thenar eminence in adults: a single-center retrospective study

• Published in: Annals of nuclear medicine 2021-10, Vol.35 (10), p.1167-1173
• Main Authors: Nakaya, Moto, Kurokawa, Ryo, Kanemaru, Noriko, Sakamoto, Naoya, Nyunoya, Keisuke, Joohyung, Youh, Kamiya, Kouhei, Cho, Shinichi, Fujita, Nana, Kamio, Satoru, Koyama, Hiroaki, Suzuki, Satoshi, Gonoi, Wataru, Abe, Osamu
• Format: Article
• Language: English
• Subjects: Adult; Adults; Age; Aged; Aged, 80 and over; Correlation coefficients; Electronic devices; Evaluation; Female; Fluorine; Fluorodeoxyglucose F18 - pharmacokinetics; Glucose; Humans; Imaging; Injection; Male; Medicine; Medicine & Public Health; Men; Middle Aged; Nuclear Medicine; Original Article; Penetration; Physiological effects; Physiology; Positron emission; Positron emission tomography; Radiology; Retrospective Studies; Sex; Young Adult
• ISSN: 0914-7187; 1864-6433
• DOI: 10.1007/s12149-021-01654-z

Objective This study evaluated the frequency, and effect of physiological 2-deoxy-2-[fluorine-18] fluoro- D -glucose (FDG) tracer injection and its association with the penetration rates of mobile devices. Methods This retrospective analysis included 213 patients (mean age ± standard deviation, 66.2 ± 14.1 years; range 23–93 years; 125 men) who underwent FDG-positron emission tomography examination. Elevated FDG activity in the thenar eminence with maximum standardized uptake value (SUVmax) ≥ 2.5 was considered positive. Differences according to age, sex, laterality, and tracer injection side were evaluated using Fisher’s exact test. Associations were assessed using Pearson’s correlation coefficient. Results Twenty-three percent (49/213) of the patients had elevated FDG activity in the thenar eminence (mean SUVmax, 3.50 ± 1.04; range 2.5–6.3), including 18 with bilateral findings. No significant difference existed according to age (