SARS-CoV-2 Neutralization with BNT162b2 Vaccine Dose 3

A third dose of the BNT162b2 vaccine was administered to 23 volunteers 8 to 9 months after the second dose, and the immune response was assessed. Local reactions were similar to those seen after the second dose. One month after the third dose, neutralization titers were 5 to 7 times as high as those...

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Bibliographic Details
Published in:New England Journal of Medicine 2021-10
Main Authors: Falsey, Ann R, Frenck, Robert W, Walsh, Edward E, Kitchin, Nicholas, Absalon, Judith, Gurtman, Alejandra, Lockhart, Stephen, Bailey, Ruth, Swanson, Kena A, Xu, Xia, Koury, Kenneth, Kalina, Warren, Cooper, David, Zou, Jing, Xie, Xuping, Xia, Hongjie, Türeci, Özlem, Lagkadinou, Eleni, Tompkins, Kristin R, Pei-Yong, Shi, Jansen, Kathrin U, Şahin, Uğur, Dormitzer, Philip R, Gruber, William C
Format: Article
Language:English
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Summary:A third dose of the BNT162b2 vaccine was administered to 23 volunteers 8 to 9 months after the second dose, and the immune response was assessed. Local reactions were similar to those seen after the second dose. One month after the third dose, neutralization titers were 5 to 7 times as high as those before the third dose, and neutralization extended to the delta variant.
DOI:10.1056/NEJMc2113468