Chronic disorders of consciousness: role of neuroimaging

Chronic disorders of consciousness are clinically challenging conditions, and advanced methods of imaging for better understanding of diagnosis and prognosis are needed. Recent functional neuroradiological studies utilizing PET and fMRI demonstrated that besides widespread neuronal loss disruption o...

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Bibliographic Details
Published in:Journal of physics. Conference series 2017-08, Vol.886 (1), p.12011
Main Authors: Kremneva, E, Sergeev, D, Zmeykina, E, Legostaeva, L, Piradov, M
Format: Article
Language:English
Subjects:
Consciousness
Disorders
Medical imaging
Physics
Positron emission
Tomography
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Summary:Chronic disorders of consciousness are clinically challenging conditions, and advanced methods of imaging for better understanding of diagnosis and prognosis are needed. Recent functional neuroradiological studies utilizing PET and fMRI demonstrated that besides widespread neuronal loss disruption of interconnection between certain cortical networks after the injury may also play the leading role in the development of behaviourally assessed unresponsiveness. Functional and structural connectivity, evaluated by neuroimaging approaches, may correlate with clinical status and may also play prognostic role. Integration of data from various diagnostic modalities is needed for further progress in this area.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/886/1/012011