Lymphatic filariasis among the Ezza people of Ebonyi State, eastern Nigeria

• Published in: Annals of Agricultural and Environmental Medicine 2005, Vol.12 (2), p.181
• Main Authors: Anosike, Jude C, Nwoke, Bertram E, Ajayi, Ezekiel G, Onwuliri, Celestine O, Okoro, Onuabuchi U, Oku, Ene E, Asor, Joe E, Amajuoyi, Oliver U, Ikpeama, Chidinma A, Ogbusu, Fidelia I, Meribe, Chidozie O
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Animals; Antigens, Helminth - analysis; Aquatic insects; Child; Child, Preschool; Comorbidity; Cultural Characteristics; Dermatitis; Elephantiasis, Filarial - diagnosis; Elephantiasis, Filarial - epidemiology; Elephantiasis, Filarial - prevention & control; Elephantiasis, Filarial - transmission; Epidemiology; Female; Fever; Filariasis; Humans; Infant; Infant, Newborn; Infectivity; Insect Bites and Stings - diagnosis; Insect Bites and Stings - epidemiology; Insect Vectors; Ivermectin; Male; Middle Aged; Nigeria - epidemiology; Risk Factors; Vector-borne diseases; Wuchereria bancrofti
• ISSN: 1232-1966; 1898-2263

A total of 1,243 Ezza people living in 10 communities of Ebonyi State, eastern Nigeria were examined between July 2002-January 2003 for lymphatic filariasis. This is the first time a filariasis survey due to Wuchereria bancrofti has been carried out in this state. Of the 1,243 persons examined, 210 (16.9 %) had W. bancrofti microfilariae. Infection varied significantly among communities and ages (p < 0.05) but not sex-related (p > 0.05). The Ezza people are predominantly farmers and professional hired labourers. There was a close association between microfilaria rate and microfilaria -density in various age groups (r = 0.812; p < 0.01). Microfilaria density is an important measure in the epidemiology, treatment and control of human filarisis in this endemic foci. Clinical signs and symptoms of the disease include elephantiasis, hydrocoele, dermatitis and periodic fever. Clinical symptoms without microfilaraemia and microfilaraemia without clinical symptoms were also observed. Of 1,603 mosquitoes dissected, Anopheles gambiae, An. funestus and Culex quinquefasciatus showed infectivity rates of 6.3 %, 5.1 % and 6.0 % respectively. The affected persons and other key informants are unaware of the cause of the disease and attributed it to witchcraft, violation of taboo, bad water and food. Intervention strategies to be integrated into the on-going Community-Directed Treatment with Ivermectin (CDTI) project are discussed.