Antihyperglycemic activity of Ficus carica leaves extracts on Streptozotocin induced diabetic rats

Antihyperglycemic activity of leave extracts of Ficus carica was evaluated on STZ induced diabetic rats. Diabetes was induced in albino Wistar rats of either sex by intraperitoneal (60mg/kg b.w.) of STZ, freshly dissolved in citrate buffer (0.01 M, pH 4.5). Ficus carica leave extract in different so...

Full description

Saved in:
Bibliographic Details
Published in:Research journal of pharmacy and technology 2021-08, Vol.14 (8), p.4151-4156
Main Authors: Roy, Tathagata, Paul, Susanta, Roy Chowdhury, Victor, Das, Arijit, Chandra, Srikanta, Das, Avik, Jana, Abhishek, Bhattacharya, Muniraj, Ghosh, Nibir
Format: Article
Language:English
Subjects:
Animals
Diabetes
Drug dosages
Experiments
Fasting
Feeds
Food
Glucose
Herbal medicine
Laboratories
Medical research
Polyuria
Rodents
Toxicity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Antihyperglycemic activity of leave extracts of Ficus carica was evaluated on STZ induced diabetic rats. Diabetes was induced in albino Wistar rats of either sex by intraperitoneal (60mg/kg b.w.) of STZ, freshly dissolved in citrate buffer (0.01 M, pH 4.5). Ficus carica leave extract in different solution (viz. petroleum ether, ethyloacetate, methanol and aqueous) were administered to diabetic rats for 9 days. The effect of extracts on blood glucose and body weight was studies on day 1st and 9th. The study showed that the ethyl acetate, methanolic and aqueous extract of Ficus sarmentosa leaves reduced blood glucose level and body weight significantly. This may justify the use of ficus species as ethanomedical medicine for treatment of diabetes mellitus.
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.52711/0974-360X.2021.00718