Two New Aporphine Alkaloids from Amoora cucullata and their Antibacterial Activity

Two new aporphine alkaloids, amocurines D and E ( 1 and 2 ), together with five known compounds ( 3–7 ), were isolated from the stems of Amoora cucullata. The structures of these compounds were elucidated based on their spectroscopic data. Compound 1 showed significant activities against Staphylococ...

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Bibliographic Details
Published in:Chemistry of natural compounds 2021-09, Vol.57 (5), p.907-910
Main Authors: Chumkaew, Parinuch, Teerapongpisan, Passakorn, Pechwang, Jaraslak
Format: Article
Language:English
Subjects:
Alkaloids
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Organic Chemistry
Plant Sciences
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Summary:Two new aporphine alkaloids, amocurines D and E ( 1 and 2 ), together with five known compounds ( 3–7 ), were isolated from the stems of Amoora cucullata. The structures of these compounds were elucidated based on their spectroscopic data. Compound 1 showed significant activities against Staphylococcus aureus (ATCC25923) and Bacillus subtilis (ATCC6633) with MIC value of 3.1 μ g/mL, whereas 2 exhibited selective antibacterial activity against B. subtilis.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-021-03508-6