Preparation of an Adduct of Levoglucosenone and Resorcinol and its in vitro Antiplatelet and Anticoagulant Activity

A procedure for the preparation of an adduct of levoglucosenone and resorcinol was developed involving ultrasonic irradiation in the presence of K 2 CO 3 and 18-crown-6 ether in toluene. In vitro anticoagulant and antiplatelet activity of the adduct was studied.

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Bibliographic Details
Published in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2021-09, Vol.57 (9), p.966-969
Main Authors: Faizullina, Liliya Kh, Khalilova, Yuliya А., Valeev, Farid А., Pavlov, Valentin N., Samorodov, Aleksandr V.
Format: Article
Language:English
Subjects:
Anticoagulants
Anticoagulants (Medicine)
Chemistry
Chemistry and Materials Science
Crown ethers
Organic Chemistry
Pharmacy
Potassium carbonate
Short Communication
Toluene
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Summary:A procedure for the preparation of an adduct of levoglucosenone and resorcinol was developed involving ultrasonic irradiation in the presence of K 2 CO 3 and 18-crown-6 ether in toluene. In vitro anticoagulant and antiplatelet activity of the adduct was studied.
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-021-03007-0