Nickel‐Catalyzed Deaminative Cross‐Coupling of Disulfides with Katritzky Pryidium Salts to Construct Sulfides

The synthesis of thioether or selenoether through the cross‐coupling of C−S or C−Se bond is a high attractive research area due to the prevalence of thioether or selenoether in pharmaceutically active compounds, bioactive natural compounds, agrochemicals, and functional materials. Herein, a novel an...

Full description

Saved in:
Bibliographic Details
Published in:Asian journal of organic chemistry 2021-10, Vol.10 (10), p.2525-2529
Main Authors: Li, Qiu‐Li, Guo, Li‐Yun, Shi, Jie, Xiang, Tong‐Xu, Li, Qing, He, Ke‐Han, Wang, Bi‐Qin, Feng, Chun, Pan, Fei
Format: Article
Language:English
Subjects:
Agrochemicals
Cross coupling
deaminative
Disulfides
Functional groups
Functional materials
Katritzky salts
Nickel
Organic chemistry
Selenides
sulfides
synthetic methods
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The synthesis of thioether or selenoether through the cross‐coupling of C−S or C−Se bond is a high attractive research area due to the prevalence of thioether or selenoether in pharmaceutically active compounds, bioactive natural compounds, agrochemicals, and functional materials. Herein, a novel and general method has been developed for the construction of C−S or C−Se bonds using Katritzky pyridinium salts with disulfides or diselenides in the presence of nickel catalyst. This procedure exhibits remarkable functional group tolerance. Under mild reaction condition, a variety of thioethers and selenoethers is successfully and efficiently obtained through deaminative cross‐coupling. A highly efficient and general method for the Nickel‐catalyzed construction of C−S or C−Se bonds using katritzky pyridinium salts with disulfides or diselenides was developed. This method exhibits good functional group tolerance. Under mild reaction condition, a variety of thioethers and selenoethers is successfully and efficiently obtained through deaminative cross‐coupling.
ISSN:2193-5807
2193-5815
DOI:10.1002/ajoc.202100438