Carotid Atherosclerosis Is Not Related to Hepatic Steatosis or Fibrosis in EDICT

The prevalence of NAFLD has increased and is associated with type 2 diabetes, obesity, insulin resistance, and metabolic syndrome. In EDICT (Efficacy and Durability of Initial Combination Therapy) we compared the efficacy of Triple (pioglitazone/ exenatide/ metformin) versus Conventional (metformin,...

Full description

Saved in:
Bibliographic Details
Published in:The American heart journal 2021-12, Vol.242, p.152-152
Main Authors: Lavrynenko, Olga, Abdul-Ghani, Muhammad, DeFronzo, Ralph
Format: Article
Language:English
Subjects:
Arteriosclerosis
Atherosclerosis
Cardiovascular diseases
Diabetes mellitus (non-insulin dependent)
Durability
Fatty liver
Fibrosis
Insulin
Insulin resistance
Metabolic disorders
Metabolic syndrome
Metformin
Pioglitazone
Steatosis
Sulfonylurea
Therapy
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The prevalence of NAFLD has increased and is associated with type 2 diabetes, obesity, insulin resistance, and metabolic syndrome. In EDICT (Efficacy and Durability of Initial Combination Therapy) we compared the efficacy of Triple (pioglitazone/ exenatide/ metformin) versus Conventional (metformin, sulfonylurea/ insulin) Therapy in newly diagnosed T2D patients. During EDICT, liver function tests were obtained in all subjects (n=318) at baseline and annually for 6 years. Plasma AST and ALT decreased significantly (p
ISSN:0002-8703
1097-6744
DOI:10.1016/j.ahj.2021.10.019