Both‐In‐One Hybrid Bacteria Suppress the Tumor Metastasis and Relapse via Tandem‐Amplifying Reactive Oxygen Species‐Immunity Responses (Adv. Healthcare Mater. 21/2021)

Synergistic Cancer Therapy In article number 2100950 by Bin Qin, Jin Sun, and co‐workers, a both‐in‐one hybrid bacteria, wherein the chemotherapeutic drug doxorubicin is integrated onto the surface of glucose dehydrogenase‐overexpressed non‐pathogenic Escherichia coli strain, potentiates stimulated...

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Bibliographic Details
Published in:Advanced healthcare materials 2021-11, Vol.10 (21), p.n/a
Main Authors: Sun, Mengchi, Ye, Hao, Shi, Qinghua, Xie, Jun, Yu, Xiang, Ling, Hao, You, Song, He, Zhonggui, Qin, Bin, Sun, Jin
Format: Article
Language:English
Subjects:
Antitumor activity
Bacteria
Doxorubicin
E coli
Glucose dehydrogenase
Immune response
Metastases
Metastasis
Reactive oxygen species
Tumors
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Summary:Synergistic Cancer Therapy In article number 2100950 by Bin Qin, Jin Sun, and co‐workers, a both‐in‐one hybrid bacteria, wherein the chemotherapeutic drug doxorubicin is integrated onto the surface of glucose dehydrogenase‐overexpressed non‐pathogenic Escherichia coli strain, potentiates stimulated systemic antitumor immune responses, thereby significantly inhibiting tumor metastasis, postsurgical regrowth, and primary/distal tumor relapse in four different tumor models.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.202170102