Synthesis of pyrimido[1,2-a]indoles (minireview)

This review considers methods for the synthesis of pyrimido[1,2- a ]indoles and their ring-fused derivatives, covering publications from the last 10 years. Depending on the synthons used for assembling the target structure, three main approaches to the synthesis of pyrimido-[1,2- a ]indoles can be d...

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Bibliographic Details
Published in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2021-10, Vol.57 (10), p.993-995
Main Authors: Nikonov, Igor L., Kopchuk, Dmitry S., Zyryanov, Grigory V., Rusinov, Vladimir L.
Format: Article
Language:English
Subjects:
Chemical reactions
Chemistry
Chemistry and Materials Science
Indoles
Organic Chemistry
Pharmacy
Pyrimidines
Synthesis
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Summary:This review considers methods for the synthesis of pyrimido[1,2- a ]indoles and their ring-fused derivatives, covering publications from the last 10 years. Depending on the synthons used for assembling the target structure, three main approaches to the synthesis of pyrimido-[1,2- a ]indoles can be distinguished: annulation of a pyrimidine ring to 2-aminoindoles, modification of other indole derivatives, and miscellaneous methods.
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-021-03012-3