Ultrafine rhenium-ruthenium nanoparticles decorated on functionalized carbon nanotubes for the simultaneous determination of antibiotic (nitrofurantoin) and anti-testosterone (flutamide) drugs

In this work, ultrafine rhenium-ruthenium nanoparticles decorated on functionalized multiwalled carbon nanotubes (Re-Ru@ f -MWCNT) were used as a new electrode platform for simultaneous electrochemical detection of nitrofurantoin (NFT, antibiotic) and flutamide (FLT, anti-testosterone) drugs. The as...

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Bibliographic Details
Published in:Journal of materials chemistry. C, Materials for optical and electronic devices Materials for optical and electronic devices, 2021-11, Vol.9 (44), p.15949-15966
Main Authors: Veerakumar, Pitchaimani, Vinothkumar, Venkatachalam, Chen, Shen-Ming, Sangili, Arumugam, Lin, King-Chuen
Format: Article
Language:English
Subjects:
Antibiotics
Carbon
Decoration
Drugs
Electrochemical analysis
Electrons
Glassy carbon
Multi wall carbon nanotubes
Nanocomposites
Nanoparticles
Raman spectroscopy
Rhenium
Ruthenium
Selectivity
Testosterone
Ultrafines
X ray photoelectron spectroscopy
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Summary:In this work, ultrafine rhenium-ruthenium nanoparticles decorated on functionalized multiwalled carbon nanotubes (Re-Ru@ f -MWCNT) were used as a new electrode platform for simultaneous electrochemical detection of nitrofurantoin (NFT, antibiotic) and flutamide (FLT, anti-testosterone) drugs. The as-prepared composite was scrutinized using various techniques, including XRD, BET, FE-SEM, FE-TEM-EDS, XPS, elemental mapping, and Raman spectroscopy. FE-TEM results revealed that Re NP (size, 1.5-2.8 ± 0.1 nm) and Ru NP (size, 1.8 ± 0.2 nm) were well-decorated on f-MWCNT. The nanocomposite was fabricated on a glassy carbon electrode (GCE) that demonstrated superior voltammetric sensing towards NFT and FLT at pH 7.0. Interestingly, Re-Ru@f-MWCNT/GCE received two linear ranges, the limit of detection, with excellent sensitivity for NFT and FLT. Also, excellent selectivity for both individual and simultaneous detection of NFT and FLT was obtained in the presence of various potential interferences. Moreover, the fabricated sensor was studied to determine NFT and FLT levels in human urine and serum with the results showing good recoveries. In this work, Re-Ru@f-MWCNT nanocomposite used as a new electrode platform for simultaneous electrochemical detection of nitrofurantoin (NFT) and flutamide (FLT) drugs.
ISSN:2050-7526
2050-7534
DOI:10.1039/d1tc02885e