OP437 Use Of Real-World Evidence In Survival Analysis Adjusting For Treatment Crossover In Cutaneous T-Cell Lymphoma

Real-World Evidence is useful for validating crossover adjustment approaches, particularly when the adjustment is required because a trial does not accurately reflect a health technology assessment (HTA)-relevant population. We use the MAVORIC trial advanced stage mycosis fungoides and Sézary syndro...

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Bibliographic Details
Published in:International journal of technology assessment in health care 2021-12, Vol.37 (S1), p.16-16
Main Authors: Hawkins, Neil, Evans, Rachel, Muszbek, Noemi, Jones, Trefor, McNamara, Linda
Format: Article
Language:English
Subjects:
Clinical medicine
Confidence intervals
Fungal infections
Health services
Lymphocytes T
Lymphoma
Mycosis
Mycosis fungoides
Oral Presentations
Patients
Population
Population (statistical)
Population statistics
Side effects
Statistical analysis
Survival
Survival analysis
T-cell lymphoma
Technology assessment
Weighting methods
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Summary:Real-World Evidence is useful for validating crossover adjustment approaches, particularly when the adjustment is required because a trial does not accurately reflect a health technology assessment (HTA)-relevant population. We use the MAVORIC trial advanced stage mycosis fungoides and Sézary syndrome cutaneous T-cell lymphoma population and data from the Hospital Episodes Statistics to explore and validate crossover adjustment methods.
ISSN:0266-4623
1471-6348
DOI:10.1017/S0266462321001045