Evaluation of the Bioactive Properties of the Mineral-Polymer Composite Calcium Phosphates – Polylactide

The bioresorption and bioactivity of hybrid composite materials containing calcium phosphates up to 60 wt.% and polylactide (PLA) were studied in situ and in vitro . The resorption dynamics of composites in the PBS model environment was determined. It was found that at calcium phosphate content equa...

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Bibliographic Details
Published in:Glass and ceramics 2021-11, Vol.78 (7-8), p.317-322
Main Authors: Petrovskaya, T. S., Toropkov, N. E., Fomenko, A. N.
Format: Article
Language:English
Subjects:
Analysis
Apatite
Biocompatibility
Biological activity
Biomedical materials
Calcium phosphate
Calcium phosphates
Ceramics
Characterization and Evaluation of Materials
Chemistry and Materials Science
Composite materials
Composites
Glass
Hybrid composites
Materials Science
Natural Materials
Polylactic acid
Polymer matrix composites
Polymers
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Summary:The bioresorption and bioactivity of hybrid composite materials containing calcium phosphates up to 60 wt.% and polylactide (PLA) were studied in situ and in vitro . The resorption dynamics of composites in the PBS model environment was determined. It was found that at calcium phosphate content equal to 40% or more apatite-type calcium phosphates are produced on the surface of composites during incubation in SBF. Composites in the studied range of compositions have a weak cytotoxic effect on the cell culture of Neuro-2a mouse neuroblastoma. The data obtained suggest dynamic resorption and bioactivity of composites in vivo .
ISSN:0361-7610
1573-8515
DOI:10.1007/s10717-021-00402-z