Construction of a novel highly electroactive nano-composite film modified with cellulose gum for the electrochemical recognition of tryptophan isomers

• Published in: Journal of electroanalytical chemistry (Lausanne, Switzerland) Switzerland), 2021-10, Vol.898, p.115636, Article 115636
• Main Authors: Du, Yongxin, Mo, Zunli, Shuai, Chao, Pei, Hebing, Wang, Jia, Chen, Ying, Yue, Ruimei, He, Simin
• Format: Article
• Language: English
• Subjects: Carbon; Carboxymethyl cellulose; Cellulose; Chemical sensors; Chiral carbon nanocomposite; Electroactivity; Electrochemical sensor; Enantiomers; Enantiorecognition; Fourier transforms; Graphene; Graphene oxide; Infrared spectroscopy; Isomers; Nanocomposites; Photoelectrons; Recognition; Sodium carboxymethyl cellulose; Tryptophan; X ray photoelectron spectroscopy
• ISSN: 1572-6657; 1873-2569
• DOI: 10.1016/j.jelechem.2021.115636

•A novel chiral carbon nanocomposite was fabricated by combining rGO-Fc and CMC.•The chiral electrochemical sensing system was constructed by functionalized graphene.•The limitation of CMC with poor enantioselectivity has been successfully broken by functionalized graphene.•The optimal condition has been tested. Ferrocene (Fc) was introduced into the layers of graphene oxide (GO) to form rGO-Fc with large surface area, high loading and high electroactivity. A chiral carbon nanocomposite rGO-Fc-CMC was synthesized via the adsorptional interaction between rGO-Fc and sodium carboxymethyl cellulose (CMC), and the successful synthesis of the chiral carbon nanocomposite (rGO-Fc-CMC) was showed by a series of characterization methods including scanning electron microscopy (SEM), Fourier transform infrared (FT-IR), X-ray photoelectron spectroscopy (XPS). The enantioselective interaction between chiral carbon nanocomposite (rGO-Fc-CMC) and tryptophan (Trp) enantiomers was detected by differential pulse voltammetry (DPV). The results demonstrated that the rGO-Fc-CMC/GCE showed a higher enantioselective capability for Trp than CMC/GCE, which can successfully break the limitation of a poor conductivity on CMC via the expansion of electrochemical signal. Therefore, designing an excellent-performance chiral carbon nanocomposite is of great significance in the construction of electrochemical sensors for chiral recognition.