Physiological and Biochemical Effects of Klebsiella oxytoca Infection on Model Organism Galleria mellonella L

In this study, the physiological and biochemical response of model insect Galleria mellonella due to Klebsiella oxytoca infection was investigated. Changes in metabolic enzyme activities such as aspartate transferase (AST), alanine transferase (ALT), alkaline phosphatase (ALP), amylase (AMYL) and ga...

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Bibliographic Details
Published in:Journal of Entomological Research Society 2021-01, Vol.23 (3), p.279-286
Main Authors: Sugeçti, Serkan, Çelik, Cihat, Büyükgüzel, Ender, Büyükgüzel, Kemal
Format: Article
Language:English
Subjects:
Alanine
Albumins
Alkaline phosphatase
Antibiotics
Antioxidants
Bacteria
Bacterial infections
Bilirubin
Enzymatic activity
Enzymes
Galleria mellonella
Hemolymph
Infections
Insects
Invertebrates
Klebsiella
Klebsiella oxytoca
Laboratories
Medical research
Metabolism
Nosocomial infections
Oxidative stress
Pathogens
Phosphatase
Physiological effects
Physiology
Uric acid
Variance analysis
Virulence
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Summary:In this study, the physiological and biochemical response of model insect Galleria mellonella due to Klebsiella oxytoca infection was investigated. Changes in metabolic enzyme activities such as aspartate transferase (AST), alanine transferase (ALT), alkaline phosphatase (ALP), amylase (AMYL) and gamma glutamyl transferase (GGT) occurred due to K. oxytoca infection. In addition, amounts of non-enzymatic antioxidant such as uric acid (UA), bilirubin (BIL) and albumin (ALB) were altered in G. mellonella hemolymph due to infection. The results obtained from this study showed that G. mellonella can be used as a model organism in the evaluation of the physiological effects of K. oxytoca infection on the host.
ISSN:1302-0250
DOI:10.51963/jers.v23i3.2069