Effect of resistance training on chronic inflammation: A systematic review and meta‐analysis

Objectives To determine the pooled effect of resistance training compared with a control, on chronic inflammation in adults through systematic review and meta‐analysis (osf.io/xastp). Methods Intervention trials that assessed resistance training versus control, on peripheral, chronic pro‐inflammator...

Full description

Saved in:
Bibliographic Details
Published in:Translational sports medicine 2021-11, Vol.4 (6), p.900-913
Main Authors: Rose, Grace Laura, Mielke, Gregore Iven, Durr, Madeleine, Schaumberg, Mia Annalies
Format: Article
Language:English
Subjects:
Chronic illnesses
cytokine
exercise
inflame
Inflammation
interleukin
Intervention
Meta-analysis
Strength training
Systematic review
Tumor necrosis factor-TNF
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objectives To determine the pooled effect of resistance training compared with a control, on chronic inflammation in adults through systematic review and meta‐analysis (osf.io/xastp). Methods Intervention trials that assessed resistance training versus control, on peripheral, chronic pro‐inflammatory markers [C‐reactive protein (CRP), interleukin (IL)‐6, and tumor necrosis factor (TNF)‐α] in adults were included, from four databases. Random‐effect meta‐analyses were conducted to calculate standardized mean differences (SMD) in post‐intervention values between groups. Meta‐regression explored the influence of age, chronic disease, body mass index, progressive resistance training (PRT), and intervention intensity, volume, duration, and “optimal prescription” on the pooled effect. Results Of 3,186 studies identified, 59 were included. Resistance training reduced CRP (SMD = −0.28; 95% CI = −0.46, −0.10), but not IL‐6 (SMD = −0.12; 95% CI = −0.31, 0.07) or TNF‐α (SMD = −0.07; 95% CI = −0.31, 0.16). Some heterogeneity was explained by interventions of lower intensity (
ISSN:2573-8488
2573-8488
DOI:10.1002/tsm2.294