Quality of Life (QoL) in Postmenopausal Breast Cancer Patients Receiving Adjuvant Hormonal Therapy

Background The primary aim of this study was to compare quality of life of postmenopausal breast cancer women receiving adjuvant hormone therapy with those not receiving. The secondary aims were to investigate impact of vitamin D status and type of hormone therapy (letrozole vs tamoxifen) on quality...

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Bibliographic Details
Published in:Indian journal of surgery 2021-06, Vol.83 (Suppl 2), p.461-467
Main Authors: Bichoo, Raouef Ahmed, Mishra, Anjali, Lal, Punita, Gyan, Chand, Agarwal, Gaurav, Agarwal, Amit, Mishra, Saroj Kanta
Format: Article
Language:English
Subjects:
Adjuvant treatment
Alfacalcidol
Breast cancer
Calcifediol
Cancer
Cancer patients
Cardiac Surgery
Care and treatment
Endocrine therapy
Health aspects
Hormones
Medicine
Medicine & Public Health
Metastasis
Neurosurgery
Original Article
Pediatric Surgery
Plastic Surgery
Postmenopausal women
Quality of life
Surgery
Tamoxifen
Thoracic Surgery
Vitamin D
Vitamin deficiency
Well being
Women
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Summary:Background The primary aim of this study was to compare quality of life of postmenopausal breast cancer women receiving adjuvant hormone therapy with those not receiving. The secondary aims were to investigate impact of vitamin D status and type of hormone therapy (letrozole vs tamoxifen) on quality of life. Settings and Design Tertiary care hospital, prospective study (March 2016 to September 2017). Patients and Methods Study included postmenopausal non-metastatic breast cancer women. Patients were divided in two groups: group 1 ( n =120) receiving adjuvant hormone therapy and group 2 ( n =93) not receiving hormone therapy. Patients filled Functional Assessment of Cancer Therapy-Breast (FACT–B) QoL questionnaire at enrolment and 6 month later. The scores were compared between the groups. Results Overall basal FACT-G ( p =0.004), FACT-B ( p =0.003), and all other quality of life subscales scores barring social well-being were significantly better in group 2 {physical well-being ( p =0.002), social well-being ( p =0.037), emotional well-being ( p =0.028), functional well-being ( p =
ISSN:0972-2068
0973-9793
DOI:10.1007/s12262-021-02766-6