Evaluation of corneal backscatter using Scheimpflug imaging in Fuchs' endothelial corneal dystrophy

• Published in: Acta ophthalmologica (Oxford, England) England), 2022-01, Vol.100 (S267), p.n/a
• Main Authors: Moscarda, Eva Josefina Núñez, Boned‐Murillo, Ana, Díaz‐Barreda, Mª Dolores, El Bakkali, Ismael Bakkali, Rivasés, Guillermo Pérez, Cisneros, Pablo, deRivas, Marta Orejudo, Karlsruher, Gisela, Del Buey Sayas, María Ángeles
• Format: Article
• Language: English
• Subjects: Cornea; Corneal dystrophy; Densitometry; Pathology; Statistical analysis
• ISSN: 1755-375X; 1755-3768
• DOI: 10.1111/j.1755-3768.2022.058

Purpose To compare corneal densitometry obtained using Scheimpflug imaging in the eyes of patients with Fuchs' Endothelial Corneal Dystrophy (FECD) versus the eyes of controls without corneal pathology. Methods An observational cross‐sectional case‐control study was carried out on 26 eyes of 14 patients with FECD, and 20 eyes of 11 controls in which corneal pathology had previously been ruled out. All patients underwent a Scheimpflug corneal tomography with Pentacam HR. An analysis of the corneal densitometry results is performed by corneal layers divided into anterior (120 µm), central and posterior (60 µm) and in different areas of concentric circumferences: 0–2 mm; 2–6 mm; 6–10 mm; 10–12 mm. Results In the FECD group, the mean backscatter of light was higher than the control group in the circumferences of 0–2 and 2‐6 mm in the anterior, central and posterior layers (p < 0.05). No statistically significant differences were found in the 6–10 and 10–12 mm circumferences. In the posterior layer, the total backscatter average was higher in the FECD group (p < 0.05). Conclusions Patients with FECD present higher corneal densitometry values than subjects without corneal pathology in the posterior layer of the cornea and in the central circumferences of the anterior, central and posterior layers.