Design and fabrication of hydrogel incorporated with copper nanoparticles loaded microsponge for antimicrobial and antioxidant activity

A hydrogel has been designed as an antimicrobial agent with low toxicity and reduced side effects. The hydrogel has been fabricated with green synthesised copper nanoparticles loaded microsponges. Here, the copper nanoparticles have been synthesised from the leaf extract of Ocimum Sanctum. This fabr...

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Bibliographic Details
Published in:Indian journal of chemical technology 2021-09, Vol.28 (5), p.645
Main Authors: Umamaheswari, R, Kothai, S
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
Antimicrobial activity
Antimicrobial agents
Antioxidants
Copper
Fabrication
Hydrogels
Nanoparticles
Particle size
Plant extracts
Side effects
Toxicity
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Summary:A hydrogel has been designed as an antimicrobial agent with low toxicity and reduced side effects. The hydrogel has been fabricated with green synthesised copper nanoparticles loaded microsponges. Here, the copper nanoparticles have been synthesised from the leaf extract of Ocimum Sanctum. This fabricated hydrogel is checked for its pH and particle size by particle size analyser (PSA). The best hydrogel is assessed through resazurin microtitre assay for its antimicrobial activity. Using DPPH assay, it is also checked for its antioxidant activity. The results show that the fabricated hydrogel incorporated with copper nanoparticles loaded microsponge act as an excellent antimicrobial gel and has shown good antioxidant potential.
ISSN:0971-457X
0975-0991
DOI:10.56042/ijct.v28i5.67625